Episode 20: Links
Absolute Science Podcast, Episode 20
Click play to listen now
How One Drug Could Prevent Both Osteoporosis and Breast Cancer
(0:20) A new study showed that Evista, a drug that is currently used to treat and prevent osteoporosis, can also prevent breast cancer.
(2:05) Evista is also called raloxifene.
(3:09) Evista has fewer side effects than tamoxifen.
(3:35) But these drugs are only for women who are at high risk of developing breast cancer.
Aside!
(4:04) An aside about a town with water polluted by aluminum sulfate where people may have an increased risk of getting Alzheimer's disease.
Back on Topic
(4:31) What does the estrogen receptor have to do with all of this?
(5:23) Breast cancer is often stimulated by estrogen. Cancer cells can have estrogen receptors on their membranes, and if so, they are called ER+.
(5:51) Weren't we talking about osteoporosis?
(6:05) Bone is constantly in flux, getting built up and broken down.
(6:47) Osteoblasts versus osteoclasts.
(7:29) Estrogen keeps osteoclasts under control.
(8:00) How can Evista have both estrogenic and anti-estrogenic effects? (This is a great article that goes into more depth than we were able to in the podcast.)
Off Topic!
(9:50) The human genome project revealed amazing complexity in humans.
Back on Topic
(10:35) Evista isn't for men, but bisphosphonates are for men and women. How do bisphosphonates work?
(11:06) Calcium and vitamin D alone don't seem to help increase bone mineral density. (But you don't want to be deficient.)
(11:30) Strength training can build bone mineral density.
(12:35) Balance exercises are important too to prevent fractures from falls.
(13:19) Weight-bearing exercise versus strength training.
(14:49) Avoid smoking and heavy drinking to prevent osteoporosis.
(14:59) Osteoporosis in men.
Break
Bumper from TWiG from Audio Pandemic Show
SEX and dieting!
(16:08) Redbook magazine article "Not in the mood for sex?"
(16:25) Exercising to the point of exhaustion decreases your desire for sex.
(17:00) The article is completely wrong in saying that you don't want to run a calorie deficit even if you are trying to lose weight. This is completely wrong!!! You can't lose weight without eating fewer calories than you burn.
(17:42) Regular, moderate exercise can increase your libido.
Closing
(18:44) Get the word out about Absolute Science, and tell all your friends. Email us at absolutescience@welltopia.com
Click play to listen now
How One Drug Could Prevent Both Osteoporosis and Breast Cancer
(0:20) A new study showed that Evista, a drug that is currently used to treat and prevent osteoporosis, can also prevent breast cancer.
(2:05) Evista is also called raloxifene.
(3:09) Evista has fewer side effects than tamoxifen.
(3:35) But these drugs are only for women who are at high risk of developing breast cancer.
Aside!
(4:04) An aside about a town with water polluted by aluminum sulfate where people may have an increased risk of getting Alzheimer's disease.
Back on Topic
(4:31) What does the estrogen receptor have to do with all of this?
(5:23) Breast cancer is often stimulated by estrogen. Cancer cells can have estrogen receptors on their membranes, and if so, they are called ER+.
(5:51) Weren't we talking about osteoporosis?
(6:05) Bone is constantly in flux, getting built up and broken down.
(6:47) Osteoblasts versus osteoclasts.
(7:29) Estrogen keeps osteoclasts under control.
(8:00) How can Evista have both estrogenic and anti-estrogenic effects? (This is a great article that goes into more depth than we were able to in the podcast.)
Off Topic!
(9:50) The human genome project revealed amazing complexity in humans.
Back on Topic
(10:35) Evista isn't for men, but bisphosphonates are for men and women. How do bisphosphonates work?
(11:06) Calcium and vitamin D alone don't seem to help increase bone mineral density. (But you don't want to be deficient.)
(11:30) Strength training can build bone mineral density.
(12:35) Balance exercises are important too to prevent fractures from falls.
(13:19) Weight-bearing exercise versus strength training.
(14:49) Avoid smoking and heavy drinking to prevent osteoporosis.
(14:59) Osteoporosis in men.
Break
Bumper from TWiG from Audio Pandemic Show
SEX and dieting!
(16:08) Redbook magazine article "Not in the mood for sex?"
(16:25) Exercising to the point of exhaustion decreases your desire for sex.
(17:00) The article is completely wrong in saying that you don't want to run a calorie deficit even if you are trying to lose weight. This is completely wrong!!! You can't lose weight without eating fewer calories than you burn.
(17:42) Regular, moderate exercise can increase your libido.
Closing
(18:44) Get the word out about Absolute Science, and tell all your friends. Email us at absolutescience@welltopia.com
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